|
週次 |
日期 |
單元主題 |
|
第1週 |
9/17 |
Master Day |
|
第2週 |
9/24 |
Seminar Intro and Demo |
|
第3週 |
10/01 |
黎芷琪 Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway. Cell. 2015 Jun 16;11(10):1591-1603
董志祥 Thymic B Cells Are Licensed to Present Self Antigens
for Central T Cell Tolerance Induction. Immunity. 2015 June 16;162 42(6): 1048–1061 |
|
第4週 |
10/08 |
李盈萱 Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein. Cell Host Microbe. 2015 Sep 9;18(3):333-44
蔡孟樵 Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling. Cell Metab. 2015 Sep 2. pii: S1550-4131(15)00391-5 |
|
第5週 |
10/15 |
張永羣 Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10;28(2):240-52.
潘妍卉 Regulation of p53 by Mdm2 E3 Ligase Function Is Dispensable in Embryogenesis and Development, but Essential in Response to DNA Damage. Cancer Cell. 2014 Aug 11;26(2):235-47 |
|
第6週 |
10/22 |
邱品慈 The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha. Cell Metab. 2014 Jul 1;20(1):172-82.
陳雅琪 Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage. Cell Rep. 2014 Nov 20;9(4):1349-60 |
|
第7週 |
10/29 |
林芷萱 Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation. Mol Cell. 2015 Apr 16;58(2):203-15.
王乙喧 Ubiquitin Signals Proteolysis-Independent Stripping of Transcription Factors. Mol cell. 2014 Mar 20；53(6):893-903 |
|
第8週 |
11/05 |
洪國哲 Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site. Cell. 2015 Aug 27;162(5):1090-100
蘇恆毅 Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1. Cell Host Microbe. 2014 Aug 13.16(2):187-200. |
|
第9週 |
11/12 |
周東霖 Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy. Cancer Cell. 2015 June 8; 27, 852–863
江奕緯 MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response. Cell Rep. 2015 Mar 11. pii: S2211-1247(15)00176-X |
|
第10週 |
11/19 |
劉芳吟 Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3. Mol Cell. 2014 Apr 10;54(1):133-46
謝凱婷 EErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis. Cell Reports. 2015 Mar 10; Pages 1599-1613 |
|
第11週 |
11/26 |
鳥取大學 Hisashi YAGI 演講 |
|
第12週 |
12/03 |
林 易 Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation Cell Metab. 2015 Aug 4;22(2):279-90
劉宸亘 Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling Cancer Cell. 2015 Apr 13;27(4):574-88 |
|
第13週 |
12/10 |
曾彥翔 Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis Cancer Cell. 2015 Apr 13;27(4):561-73
王栩沅 Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis. Cancer Cell. 2015 Jul 13;28(1):42-56 |
|
第14週 |
12/17 |
張育瑄 Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis. 2015 Feb 9;27(2):271-85
卞毓嘉 14-3-3z Turns TGF-b’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2. Cancer Cell. 2015 Feb 9;27(2)177-92 |
|
第15週 |
12/24 |
預備週 |
|
第16週 |
12/31 |
預備週 |
|
第17週 |
01/07 |
合班上課 |